Browsing by Author "Araya-Castro, Paulina"
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Publication Item Dataset: Effect of Intraoral Photobiomodulation on Nutritional Outcomes in Patients Undergoing Hematopoietic Cell Transplantation. A Secondary Analysis of a Randomized Controlled Trial(Universidad del Desarrollo, Facultad de Medicina Clínica Alemana; Clínica Dávila; Facultad de Ciencias de la Rehabilitación, Universidad Andrés Bello, 2026) Quintiliano, Daiana; López-Espinoza, Tomás; Fabia Valdatta, Valentina; Araya-Castro, Paulina; Zerega, María Verónica; Santibáñez, Leslie; Sacomori, CinaraPublication Photobiomodulation therapy to prevent oral mucositis and functional impairment in adult patients with haematological cancer undergoing haematopoietic stem cell transplantation: randomised trial protocol(2024) López-Espinoza, Tomas; Sacomori, Cinara; Araya-Castro, Paulina; Quintiliano Scarpelli Dourado, Daiana; Roldán, Paola; Peña- Espinoza, Mónica; Ferreira de Rezende, Laura; López- Vidal, HernánIntroduction Oral mucositis is a highly prevalent condition in individuals treated for haematological neoplasms, primarily during haematopoietic stem cell transplantation (HSCT). The condition is known to delay recovery processes, increasing the risk of infection, the number of interventions and the length of hospital stays. The proposed Photobiomodulation Therapy for Oral Mucositis and Functional Impairment Transplantation Trial aims to assess the effectiveness and acceptability of using photobiomodulation in the oral cavity to prevent oral mucositis and functional impairment in adult patients undergoing HSCT. Methods and analysis This is an assessor- blinded and statistician- blinded, parallel- group randomised controlled clinical trial (photobiomodulation vs control group). Participants and setting: 30 patients, aged 18–65 years, with haematological neoplasms undergoing HSCT at the Clínica Dávila Oncology and Bone Marrow Transplant Unit. Primary outcome measures: oral mucositis will be assessed daily using the WHO grading scale, beginning on the day of transplant through day 20 post- transplant. Researchers will assess functional capacity using a 2 min step test, handgrip strength with the Jamar digital dynamometer, lower limb strength using a 30’ sit- to- stand test and quality of life with the Functional Assessment of Cancer Therapy- Bone Marrow Transplantation Questionnaire. Acceptability will be assessed by logging treatment adherence and using a Visual Analogue Scale. Assessments will occur at two time points (1): on admission to the transplant unit, before starting the conditioning regimen and (2) on the day of discharge. Intervention: three times per week photobiomodulation therapy using a diode laser device will begin the first day of conditioning and continue through day 3 post-transplant. Ethics and dissemination The Clínica Dávila and Universidad del Desarrollo Clinical Research Ethics Committees approved this study in accordance with the Helsinki Declaration. Patients’ informed consent will be required. The dissemination strategy includes publication in scientific journals as well as presentations in the media and at conferences.Item Pre-rehabilitation of the pelvic floor before radiation therapy for cervical cancer: a pilot study(2020) Sacomori, Cinara; Araya-Castro, Paulina; Diaz-Guerrero, Paulette; Ferrada, Ingrid Alanis; Martínez-Varas, Angélica Claudia; Zomkowski, KamillaIntroduction and hypothesis The objective was to evaluate pelvic floormuscle (PFM) function regarding strength, activation and incontinence, approximately 1 month before and after radiation therapy in women with cervical cancer. Methods This was a pilot study of 49 women with cervical cancer at stages I to III. Thesewomen attended an educational session with a physical therapist who taught themto performpreventive pelvic floormuscle exercises (PFMEs; slowand fast contractions and the “knack”) at home before, during and after radiation therapy. The women received instructions for performing PFME prior to radiation therapy. The modified Oxford scale, electromyography (EMG), the International Consultation on Incontinence Questionnaire Short Form to assess urinary incontinence and two questions for faecal and gas incontinence were used. Results Twenty-eight women (57%; mean age = 44 years, range 27–66) completed the study, 21 (43%) were lost to follow-up. There was no significant change from baseline to post-radiation therapy in muscle strength, EMG records and incontinence (p > 0.05). The median of PFM strength was equal at baseline and after intervention (median = 2; IQR = 1). Conclusions The results of this study suggest that pre-rehabilitation teaching PFMEs might be a protective factor for preserving PFM strength and preventing incontinence 1 month after radiation therapy. It is a feasible intervention.Publication Work Ability, Physical Activity Level, and Fatigue in Breast Cancer Survivors in Chile: A Cross-Sectional Study. Dataset(Universidad del Desarrollo. Facultad de Medicina, 2026) Ortiz-Orellana, Fernanda; Sacomori, Cinara; Leppe, Jaime; Bergmann, Anke; Fry, Hannah; Araya-Castro, Paulina