• Efficacy of gamification-based smartphone application for weight loss in overweight and obese adolescents: study protocol for a phase II randomized controlled trial 

  Timpel, Patrick; Henpin Yue Cesena, Fernando; Silva Costa, Cristiane da; Dorigatti Soldatelli, Matheus; Gois Jr., Emanuel; Castrillon, Eduardo; Jaime Díaz, Lina Johana; Repetto, Gabriela; Castillo Yermenos, Raul E.; Fanah, Hagos; Pacheco-Barrios, Kevin; Musallam, Wafaa; Braid, Zilda; Nesreen, Khidir; Longo Roepke, Roberta Muriel; Romo Guardado, Marcela (2018)

  Background: Overweight and obesity are significant public health concerns that are prevalent in younger age cohorts. Preventive or therapeutic interventions are difficult to implement and maintain over time. On the other ...
• Quantifying the ecological diversity and health of online news 

  Elejalde, Erick; Ferres, Leo; Herder, Eelco; Bollen, Johan (2018)

  Even in developed countries with an active free press, news coverage can be dominated by only a few players. This can lead to a reduction of topical and community diversity. Ownership structures might further limit coverage ...
• Ideas, Leaders, and Institutions in 19th century Chile 

  Larroulet Vignau, Cristián; Couyoumdjian, Juan Pablo (2018)

  Institutions matter for economic growth. Thus, the leaders who help to develop institutions, and their ideas and beliefs, must play a central role in any narrative that seeks to explain such growth. This leads to the ...
• A User-Centered Mobile Cloud Computing Platform for Improving knowledge Management in Small-to-Medium Enterprises in the Chilean Construction Industry 

  Núñez, Daniela; Ferrada, Ximena; Neyem, Andrés; Serpell, Alfredo; Sepúlveda, Marcos (2018)

  Knowledge management (KM) is a key element for the development of small-to-medium enterprises (SMEs) in the construction industry. This is particularly relevant in Chile, where this industry is composed almost entirely ...
• Near-apneic ventilation decreases lung injury and fibroproliferation in an ARDS model with ECMO 

  Araos, Joaquin; Alegría, Leyla; Garcia, Patricio; Cruces, Pablo; Soto, Dagoberto; Erranz, Benjamín; Amthauer, Macarena; Salomon, Tatiana; Medina, Tania; Rodríguez, Felipe; Ayala, Pedro; Borzone, Gisella R.; Meneses, Manuel; Damiani, Felipe; Retamal, Jaime; Cornejo, Rodrigo; Bugedo, Guillermo; Bruhn, Alejandro (2018)

  Rationale: There is wide variability in mechanical ventilation settings during ECMO in ARDS patients. Although lung rest is recommended to prevent further injury, there is no evidence to support it. Objectives: To ...
• Establishing Principles for Bushfire Resilient Urban Planning 

  Gonzalez-Mathiesen, Constanza (2018)

  The aim of this study is to elaborate on the built and natural environment disciplines’ potential to develop applied understandings of resilience, using the example of land-use planning design guides in bushfire prone ...
• Los partidos políticos y su relación con el régimen de gobierno en Chile 

  Andrades Rivas, Eduardo (2016)

  Cuando se estudia la Historia Constitucional de Chile, una de las cuestiones que más polémica genera, es la que aborda la relación entre los Partidos y el régimen político vigente. Los claros y oscuros de esta ambivalente ...
• “La incultura en que España mantenía a sus colonias”, Dos tópicos del mito fundacional republicano en Chile 

  Andrades Rivas, Eduardo (2018)

  El artículo examina un tópico clásico de la historiografía jurídica del siglo XIX, la afirmación de que la Monarquía Hispánica mantenía a los reinos americanos, sus supuestas colonias, en la ignorancia y el analfabetismo, ...
• Characterization of diabetic neuropathy progression in a mouse model of type 2 diabetes mellitus 

  Gregorio, Cristian De; Contador, David; Campero, Mario; Ezquer, Marcelo; Ezquer, Fernando (2018)

  Diabetes mellitus (DM) is one of most common chronic diseases with an increasing incidence in most countries. Diabetic neuropathy (DN) is one of the earliest and main complications of diabetic patients, which is ...
• Shopping mall attraction and social mixing at a city scale 

  Beiró, Mariano G.; Bravo, Loreto; Caro, Diego; Ferres, Leo; Graells-Garrido, Eduardo; Cattuto, Ciro (2018)

  In Latin America, shopping malls seem to offer an open, safe and democratic version of the public space. However, it is often difficult to quantitatively measure whether they indeed foster, hinder, or are neutral with ...
• On the nature of real and perceived bias in the mainstream media 

  Elejalde, Erick; Ferres, Leo; Herder, Eelco (2018)

  News consumers expect news outlets to be objective and balanced in their reports of events and opinions. However, there is a growing body of evidence of bias in the media caused by underlying political and socio-economic ...
• Understanding news outlets’ audience-targeting patterns 

  Ferres, Leo; Elejalde, Erick; Schifanella, Rossano (2019)

  The power of the press to shape the informational landscape of a population is unparalleled, even now in the era of democratic access to all information outlets. However, it is known that news outlets (particularly more ...
• Power structure in Chilean news media 

  Bahamonde, Jorge; Bollen, Johan; Elejalde, Erick; Ferres, Leo; Poblete, Bárbara (2018)

  Even democracies endowed with the most active free press struggle to maintain diversity of news coverage. Consolidation and market forces may cause only a few dominant players to control the news cycle. Editorial policies ...
• Differential Methylation of Genomic Regions Associated with Heteroblasty Detected by M&M Algorithm in the Nonmodel Species Eucalyptus globulus Labill 

  Hasbún, Rodrigo; Iturra, Carolina; Bravo, Soraya; Rebolledo-Jaramillo, Boris; Valledor, Luis (2016)

  Epigenetic regulation plays important biological roles in plants, including timing of flowering and endosperm development. Little is known about the mechanisms controlling heterochrony (the change in the timing or rate of ...
• Using Compressed Suffix-Arrays for a Compact Representation of Temporal-Graphs 

  Brisaboa, Nieves R.; Caro, Diego; Fariña, Antonio; Rodríguez, M. Andrea (2018)

  Temporal graphs represent binary relationships that change along time. They can model the dynamism of, for example, social and communication networks. Temporal graphs are defined as sets of contacts that are edges tagged ...
• Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA 

  Rebolledo-Jaramillo, Boris; Su, Marcia Shu-Wei; Stoler, Nicholas; McElhoe, Jennifer A; Dickins, Benjamín; Blankenberg, Daniel; Korneliussen, Thorfinn S.; Chiaromonte, Francesca; Nielsen, Rasmus; Holland, Mitchell M. (2014)

  The manifestation of mitochondrial DNA (mtDNA) diseases depends on the frequency of heteroplasmy (the presence of several alleles in an individual), yet its transmission across generations cannot be readily predicted owing ...
• Cis-regulatory elements are harbored in Intron5 of the RUNX1 gene 

  Rebolledo-Jaramillo, Boris; Alarcon, Ricardo A.; Fernández, Valentina I.; Gutiérrez, Soraya E. (2014)

  Background: Human RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; ...
• Controlling for contamination in re-sequencing studies with a reproducible web-based phylogenetic approach 

  Dickins, Benjamin; Rebolledo-Jaramillo, Boris; Su, Marcia Shu-Wei; Paul, Ian M.; Blankenberg, Daniel; Stoler, Nicholas; Makova, Kateryna D.; Nekrutenko, Anton (2014)

  Polymorphism discovery is a routine application of next-generation sequencing technology where multiple samples are sent to a service provider for library preparation, subsequent sequencing, and bioinformatic analyses. The ...
• Function of GATA Factors in the Adult Mouse Liver 

  Zheng, Rena; Rebolledo-Jaramillo, Boris; Zong, Yiwei; Wang, Liqing; Russo, Pierre; Hancock, Wayne; Stanger, Ben Z.; Hardison, Ross C.; Blobel, Gerd A. (2013)

  GATA transcription factors and their Friend of GATA (FOG) cofactors control the development of diverse tissues. GATA4 and GATA6 are essential for the expansion of the embryonic liver bud, but their expression patterns and ...
• RNA-DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA 

  Bar-Yaacov, Dan; Avital, Gal; Levin, Liron; Richards, Allison L.; Hachen, Naomi; Rebolledo-Jaramillo, Boris; Nekrutenko, Anton; Zarivach, Raz; Mishmar, Dan (2013)

  RNA transcripts are generally identical to the underlying DNA sequences. Nevertheless, RNA-DNA differences (RDDs) were found in the nuclear human genome and in plants and animals but not in human mitochondria. Here, by ...

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