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Browsing Dirección de Investigación by Subject "Daptomycin"

Browsing Dirección de Investigación by Subject "Daptomycin"

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  • Reyes, Jinnethe; Panesso, Diana; Mishra, Nagendra; Cruz, Melissa; Munita, José; Singh, Kavindra; Yeaman, Michael; Murray, Barbara; Shamoo, Yousif; Garsin, Danielle; Bayer, Arnold; Arias, César A. (The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America, 2015)
    Daptomycin is a lipopeptide antibiotic that is used clinically against many gram-positive bacterial pathogens and is considered a key frontline bactericidal antibiotic to treat multidrug-resistant enterococci. Emergence ...
  • Munita, Jose; Murray, Barbara; Arias, Cesar (Elsevier, 2014)
    Treatment of severe infections caused by vancomycin-resistant enterococci (VRE) is challenging due to the scarcity of reliable therapeutic alternatives. In this context, daptomycin (DAP), a lipopeptide antibiotic, has ...
  • Panesso, Diana; Reyes, Jinnethe; Gaston, Elizabeth; Deal, Morgan; Londoño, Alejandra; Nigo, Masayuki; Munita, Jose; Miller, William; Shamoo, Yousif; Tran, Truc; Arias, Cesar (American Society for Microbiology, 2015)
    We have shown previously that changes in LiaFSR, a three-component regulatory system predicted to orchestrate the cell membrane stress response, are important mediators of daptomycin (DAP) resistance in enterococci. Indeed, ...

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