Intracerebral stem cell administration inhibits relapse-like alcohol drinking in rats
| dc.contributor.author | Israel, Yedy | |
| dc.contributor.author | Ezquer, Fernando | |
| dc.contributor.author | Quintanilla, María Elena | |
| dc.contributor.author | Morales, Paola | |
| dc.contributor.author | Ezquer, Marcelo | |
| dc.contributor.author | Herrera-Marschitz, Mario | |
| dc.date.accessioned | 2017-10-04T15:41:42Z | |
| dc.date.available | 2017-10-04T15:41:42Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Study describes the blockade of relapse-like alcohol drinking by mesenchymal stem cells (MSCs). High alcohol-intake bred rats consumed alcohol for 3 months and were subjected to repeated alcohol deprivations for 7-14 days, followed by alcohol reaccess. Upon reaccess, animals consumed 2.2 g alcohol/kg in 60 minutes. A single intra-cerebroventricular MSC administration inhibited relapse-like drinking up to 80-85% for 40 days (P < 0.001). An alcohol-use-disorder was prevented. | |
| dc.format.extent | 4 | |
| dc.identifier.citation | Israel Y, Ezquer F, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M. Intracerebral Stem Cell Administration Inhibits Relapse-like Alcohol Drinking in Rats. Alcohol Alcohol. 2017 Jan;52(1):1-4. | |
| dc.identifier.uri | http://hdl.handle.net/11447/1693 | |
| dc.identifier.uri | http://dx.doi.org/10.1093/alcalc/agw068 | |
| dc.language.iso | en_US | |
| dc.publisher | Oxford University Press | |
| dc.subject | Ethanol | |
| dc.subject | Stem cells | |
| dc.subject | Alcohol drinking | |
| dc.subject | Rats | |
| dc.title | Intracerebral stem cell administration inhibits relapse-like alcohol drinking in rats | |
| dc.type | Artículo |
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