Para entender la acción del cortisol en inflamación aguda: una mirada desde la glándula suprarrenal hasta la célula blanco

dc.contributor.author	Guerrero, Julia
dc.date.accessioned	2017-08-30T14:12:58Z
dc.date.available	2017-08-30T14:12:58Z
dc.date.issued	2017
dc.description.abstract	Glucocorticoids (cortisol in humans) are essential for numerous biological functions. Among critically ill patients, therapy with cortisol has gained strength in recent years, but clinical results have been mixed. A series of events, that may explain the diversity of clinical responses, occur from the synthesis of cortisol in the adrenal gland to the activation of the cortisol receptor by the hormone when it enters the nucleus of the target cell. Some of these events are revised; a proposition for identifying critically ill patients who may benefit with this therapy is suggested.
dc.format.extent	10
dc.identifier.citation	Rev Med Chile 2017; 145: 230-239
dc.identifier.uri	http://hdl.handle.net/11447/1626
dc.identifier.uri	http://dx.doi.org/10.4067/S0034-98872017000200011
dc.language.iso	spa
dc.publisher	Sociedad Medica de Santiago
dc.subject	Adrenal Insufficiency
dc.subject	Critical Care
dc.subject	Hydrocortisone
dc.subject	Receptor, Glucocorticoid
dc.title	Para entender la acción del cortisol en inflamación aguda: una mirada desde la glándula suprarrenal hasta la célula blanco
dc.title.alternative	Understanding cortisol action in acute inflammation. A view from the adrenal gland to the target cell
dc.type	Artículo

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