Establishing a program for individuals at high risk for breast cancer

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dc.contributor.authorCadiz, Fernando
dc.contributor.authorKuerer, Henry
dc.contributor.authorPuga, Julio
dc.contributor.authorCamacho, Jamile
dc.contributor.authorCunill, Eduardo
dc.contributor.authorArun, Banu
dc.date.accessioned2017-04-12T12:17:36Z
dc.date.available2017-04-12T12:17:36Z
dc.date.issued2013
dc.description.abstractOur need to create a program for individuals at high risk for breast cancer development led us to research the available data on such programs. In this paper, we summarize our findings and our thinking process as we developed our own program. Breast cancer incidence is increasing worldwide. Even though there are known risk factors for breast cancer development, approximately 60% of patients with breast cancer have no known risk factor, although this situation will probably change with further research, especially in genetics. For patients with risk factors based on personal or family history, different models are available for assessing and quantifying risk. Assignment of risk levels permits tailored screening and risk reduction strategies. Potential benefits of specialized programs for women with high breast cancer risk include more cost -effective interventions as a result of patient stratification on the basis of risk; generation of valuable data to advance science; and differentiation of breast programs from other breast cancer units, which can result in increased revenue that can be directed to further improvements in patient care. Guidelines for care of patients at high risk for breast cancer are available from various groups. However, running a high-risk breast program involves much more than applying a guideline. Each high-risk program needs to be designed by its institution with consideration of local resources and country legislation, especially related to genetic issues. Development of a successful high-risk program includes identifying strengths, weaknesses, opportunities, and threats; developing a promotion plan; choosing a risk assessment tool; defining "high risk"; and planning screening and risk reduction strategies for the specific population served by the program. The information in this article may be useful for other institutions considering creation of programs for patients with high breast cancer risk.
dc.format.extent14
dc.identifier.citationJournal of Cancer, 2013, 4(5):433-446
dc.identifier.urihttp://hdl.handle.net/11447/1133
dc.identifier.urihttp://dx.doi.org/10.7150/jca.6481
dc.language.isoen_US
dc.publisherIvyspring International Publisher
dc.subjectBRCA
dc.subjectBreast cancer
dc.subjectgenetic counseling
dc.subjectpreventive therapy
dc.subjectprophylactic surgery
dc.titleEstablishing a program for individuals at high risk for breast cancer
dc.typeArtículo

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