Síndrome de nistagmo vertical hacia abajo: Reporte de 2 casos y revisión de la literatura
Date
2016
Type:
Artículo
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8
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Publisher
Sociedad Chilena de Otorrinolaringología, Medicina y Cirugía de Cabeza y Cuello
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Abstract
Downbeat nystagmus syndrome (DBN) is a frequent form of acquired fixation nystagmus, it presents with persisting nistagmus with fast phases directed downward, dizziness, oscillopsia and gait disturbances. It is considered a vestibulocerebellar disorder due to a bilateral defect of the Purkinje cells in the cerebellar flocculus. Most reported causes are degenerative disorders of the cerebellum and cerebellar ischemia, nevertheless the etiology remains unknown in a large percentage of patients (idiopathic form). DBN may present in a broader context of somatosensory neuropathy and cerebellar ataxia as in CANVAS syndrome. Therapeutic measures includes avoiding the supine and prone position when resting, vestibular rehabilitation, and pharmacologic treatment with aminopyridines, among others. In this article we present two cases of DBN and review of literature.
Description
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Citation
Rev. Otorrinolaringol. Cir. Cabeza Cuello 2016; 76: 63-70
Keywords
Downbeat nystagmus, cerebellar ataxia, vestibular rehabilitation, aminopyridine