Gallardo, NataliaValenzuela, OmarIbáñez, Sebastián2016-05-162016-05-162015Gallardo C N, Valenzuela L O, Ibáñez V S. Neumomediastino y necrosis cutánea en asociación a dermatomiositis: presentación de un caso clínico y revisión de la literatura [Pneumomediastinum and cutaneous necrosis in dermatomyositis: Report of one case]. Rev Med Chil. 2015 Jan;143(1):120-3http://hdl.handle.net/11447/250http://dx.doi.org/10.4067/S0034-98872015000100017We report a 37 years old male with a dermatomyositis treated with oral cyclophosphamide. He was admitted to the hospital due to a zone of skin necrosis with purulent exudate, located in the second left toe. A complete blood count showed a leukocyte count of 2,600 cells/mm3. A Chest CAT scan showed a pneumomediastinum with emphysema of adjacent soft tissue. Cyclophosphamide was discontinued and leukocyte count improved. The affected toe was amputated and a chest CAT scan showed a partial resolution of the pneumomediastinum. We discuss and review the pathogenesis, clinical presentation and management of pneumomediastinum and cutaneous necrosis in association with dermatomyositis.spaDermatomyositisMediastinal emphysemaSkin ulcerVascular diseasesArtículo