Fajre, XimenaAspillaga, MariaMcNab, MariaNavarrete, JorgeSanhueza, VeronicaBenedetto, Juana2017-05-102017-05-102016Rev. méd. Chile vol.144 no.5 Santiago May 2016http://hdl.handle.net/11447/1218http://dx.doi.org/10.4067/S0034-98872016000500017Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of lips and buccal mucosa, often accompanied with melanonychia. The main concern with this condition is to rule out other differential diagnosis with systemic repercussions and similar hyperpigmentation patterns, such as Peutz-Jeghers syndrome, adrenal insufficiency and melanoma. We report a 58-year-old female with a 20-year history of Sjögren’s syndrome, presenting with melanonychia and hyperpigmentation in the buccal mucosa. She had no relevant medication history and is a non-smoker. The patient denied any other symptoms. The histopathology confirmed the diagnosis of Laugier-Hunziker syndrome.4spaAutoimmunityHyperpigmentationMouth MucosaPigmentation DisordersSjogren´s syndromeArtículo