Simar, ShelbyTran, TrucRydell, KirstenPanesso, DianaContreras, GermanMunita, Jose M.Cifuentes. RenzoAbbo, LilianSahasrabhojane, PranotiDinh, AnAxell-House, DierdreSavidge, TorShelburne, SamuelHanson, BlakeArias, Cesar2024-05-272024-05-272023Simar SR, Tran TT, Rydell KB, Panesso D, Contreras GA, Munita JM, Cifuentes RO, Abbo LM, Sahasrabhojane P, Dinh AQ, Axell-House DB, Savidge T, Shelburne SA, Hanson BM, Arias CA. Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida. Antimicrob Agents Chemother. 2023 Jan 24;67(1):e0128422. doi: 10.1128/aac.01284-22https://hdl.handle.net/11447/8895In the United States, vanB-mediated resistance in enterococci is rare. We characterized three sequence type (ST) 6, vancomycin-resistant Enterococcus faecalis isolates causing bacteremia in unique patients in spatiotemporally distinct settings. Isolates were recovered between 2018 and 2020 in two cities in the United States (Houston, TX; Miami, FL). The isolates harbored the vanB operon on a chromosomally located Tn1549 transposon, and epidemiological data suggested multiple introductions of the vanB gene cluster into ST6 E. faecalis.enEnterococcusVREAntimicrobial resistanceArticlehttps://doi.org/10.1128/aac.01284-22