Larrondo, JorgeGosch, MariannePena, CamilaCabrera, RaúlJeraldo, CeciliaCastro, AlexMcMichael, Amy2022-04-122022-04-122021Larrondo J, Gosch M, Peña C, Cabrera R, Jeraldo C, Castro A, McMichael AJ. Do not forget to check the scalp in systemic light-chain amyloidosis. J Am Acad Dermatol. 2021 Mar;84(3):e121-e122. doi: 10.1016/j.jaad.2020.06.053https://doi.org/10.1016/j.jaad.2020.06.053http://hdl.handle.net/11447/5979Systemic light chain amyloidosis (AL) is a nonproliferative plasma cell disorder in which fragments of immunoglobulin deposit in tissues. Clinical manifestations are often nonspecific, making diagnosis challenging.Biopsy of involved organs is the gold standard to confirm the diagnosis; however, internal organ biopsy may beunsafe because of a significant risk of bleeding.1 New techniques to improve diagnosis are needed.enAlopeciaAmyloidDermoscopy-guided biopsyLight-chain systemic amyloidosisTrichoscopyArticle