Guiloff, RodrigoIñiguez, MagalyPrado, TomásFigueroa, FranciscoOlavarría, NicolásCarrasco, EduardoErgas, EnriqueSalgado, MartínLyman, Stephen2024-06-052024-06-052023Guiloff R, Iñiguez M, Prado T, Figueroa F, Olavarría N, Carrasco E, Ergas E, Salgado M, Lyman S. Cross-cultural adaptation and validation of the KOOS, JR questionnaire for assessing knee osteoarthritis in Spanish-speaking patients. Knee Surg Sports Traumatol Arthrosc. 2023 Dec;31(12):5413-5419. doi: 10.1007/s00167-023-07577-8.https://hdl.handle.net/11447/9040Purpose The present study aims to translate, adapt and validate a Spanish version of the Knee Injury and OsteoarthritisOutcome Score, Joint Replacement (KOOS, JR), including a reliability and validity analysis in patients with knee osteoar-thritis (OA).Methods This study conducted a prospective validation study following the six stages of the “Guidelines for the Process ofCross-Cultural Adaptation of Self-Report Measures”. Psychometric testing was conducted in patients with knee osteoarthritis.Subjects answered the Spanish KOOS, JR (S-KOOS, JR) and a validated Spanish Oxford Knee Score (S-OKS). Retest wasconducted at 10 days. Acceptability, floor and ceiling effect, internal consistency (Cronbach’s α), reproducibility (mixed-effect model coefficient [MEMC]) and construct validity (Spearman’s correlation; p = 0.05) were assessed.Results Forty-one patients (mean age: 65.6 ± 5.39; 48.8% female) participated in the study. All patients (100%) answeredboth scores during the first assessment and 38 (92.7%) during the second assessment. All patient-reported outcomes measureswere answered completely (100%). The S-KOOS, JR resulted in 100% acceptability when answered. There were no ceilingor floor effects detected. The Cronbach’s α for the S-KOOS, JR was 0.927 and its MEMC was 0.852 (CI 95% 0.636–1.078).The Spearman’s correlation between the S-KOOS, JR and the S-OKS was 0.711 (CI 0.345–0.608; p < 0.001) and 0.870 (CI0.444–0.651; p < 0.001) for the first and second assessments, respectively.Conclusion The S-KOOS, JR has very high internal consistency and reproducibility, with a high correlation with the S-OKS;it is a reliable and valid instrument for characterising Spanish-speaking patients suffering from knee OA.Level of evidence IV.7 p.enAdaptationKnee osteoarthritisKnee replacementPatient-reported outcome measureSpanishValidation.KOOSKOOS JRArticlehttps://doi.org/10.1007/s00167-023-07577-8