Sharma, AdityaLuvsansharav, Ulzii-OrishikhPaul, PrabasajLutgring, JosephCall, DouglasOmulo, SylviaLaserson, KaylaAraos, RafaelMunita, JoséVerani, JenniferChowdhury, FahmidaMah-E Muneer, SyedaEspinosa-Bode, AndrésRamay, BrookeCordon, CeliaKumar, GirishBhatnagar, TarunGupta, NeilPark, BenjamínSmith, Rachel M.2022-01-102022-01-102021Sharma A, Luvsansharav UO, Paul P, Lutgring JD, Call DR, Omulo S, Laserson K, Araos R, Munita JM, Verani J, Chowdhury F, Muneer SM, Espinosa-Bode A, Ramay B, Cordon-Rosales C, Kumar CPG, Bhatnagar T, Gupta N, Park B, Smith RM. Multi-country cross-sectional study of colonization with multidrug-resistant organisms: protocol and methods for the Antibiotic Resistance in Communities and Hospitals (ARCH) studies. BMC Public Health. 2021 Jul 16;21(1):1412. doi: 10.1186/s12889-021-11451-yhttps://doi.org/10.1186/s12889-021-11451-yhttp://hdl.handle.net/11447/5400Background: Antimicrobial resistance is a global health emergency. Persons colonized with multidrug-resistant organisms (MDROs) are at risk for developing subsequent multidrug-resistant infections, as colonization represents an important precursor to invasive infection. Despite reports documenting the worldwide dissemination of MDROs, fundamental questions remain regarding the burden of resistance, metrics to measure prevalence, and determinants of spread. We describe a multi-site colonization survey protocol that aims to quantify the populationbased prevalence and associated risk factors for colonization with high-threat MDROs among community dwelling participants and patients admitted to hospitals within a defined population-catchment area.enBangladeshCross-Sectional StudiesDrug Resistance, Multiple, BacterialHospitalsGuatemalaChileHumansIndiaKenyaMethicillin-Resistant Staphylococcus aureusMultilocus Sequence TypingStaphylococcal Infections / drug therapyStaphylococcal Infections / epidemiologyArticle