Munita, JoséMishra, Nagendra N.Alvarez, DanyaTran, Truc TDiaz, LorenaPanesso, DianaReyes, JinnetheMurray, Barbara EAdachi, Javier ABayer, Arnold SArias, Cesar A2021-11-032021-11-032014Clinical Infectious Diseases, 2014, 59(9):1277-80http://dx.doi.org/10.1093/cid/ciu642http://hdl.handle.net/11447/5007High-dose daptomycin (DAP) therapy failed in a neutropenic patient with bloodstream infection caused by a DAP-susceptible Enterococcus faecium (minimum inhibitory concentration, 3 µg/mL) harboring genetic changes associated with DAP resistance, with persistent bacteremia and selection of additional resistances. Daptomycin monotherapy should be used cautiously against DAP-susceptible E. faecium strains with minimum inhibitory concentrations >2 µg/mL.enEnterococcus faeciumDaptomycinResistanceTreatment failureArticle