Significant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinib

Berna, RonaldHasbún, María TrinidadAdams, DeniseMoon, A.Treat, J. R.2025-01-232025-01-232024Berna R, Hasbun T, Adams D, Moon AT, Treat JR. Significant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinib. Pediatr Dermatol. 2024 Sep-Oct;41(5):936-937. doi: 10.1111/pde.15666https://hdl.handle.net/11447/9705Giant congenital melanocytic nevi (GCMN) can be cosmetically significant and can lead to melanoma. There is no standard pharmacologic treatment for GCMN. We present the case of an 8-year-old female with kaposiform lymphangiomatosis caused by an NRAS mutation whose nevus spilus-type GCMN improved on oral selumetinib.enSignificant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinibArticlehttps://doi.org/10.1111/pde.15666