Ormazábal-Toledo, RodrigoCampodónico, PaolaContreras, Renato2016-12-152016-12-152011Organic Letters, 2011, vol. 13, n° 4, p. 822-824http://hdl.handle.net/11447/895http://dx.doi.org/10.1021/ol103033jIt is proposed that the electrofugality of a fragment within a molecule is determined by its group nucleophilicity. The variation of electrofugality should be tightly related to the electron releasing ability of the substituent attached to the electrofuge moiety. This contribution closes the set of relationships between philicity and fugality quantities: while nucleofugality appears related to the group electrophilicity of the leaving group, electrofugality is related to the group nucleophilicity of the permanent group.en-USNucleophilic-substitution ReactionsPolar Organic-reactivityNucleofugalityScalesIndexCombinationsParameterKeyArtículo