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Modeling the Spread of Tuberculosis in Semiclosed Communities

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dc.contributor.author Herrera, Mauricio
dc.contributor.author Bosch, Paul
dc.contributor.author Nájera, Manuel
dc.contributor.author Aguilera, Ximena
dc.date.accessioned 2016-06-30T20:23:08Z
dc.date.available 2016-06-30T20:23:08Z
dc.date.issued 2013
dc.identifier.citation Computational and Mathematical Methods in Medicine, 2013, Article ID 648291, 19 pages
dc.identifier.uri http://hdl.handle.net/11447/662
dc.identifier.uri http://dx.doi.org/10.1155/2013/648291
dc.description.abstract We address the problem of long-term dynamics of tuberculosis (TB) and latent tuberculosis (LTB) in semiclosed communities. These communities are congregate settings with the potential for sustained daily contact for weeks, months, and even years between their members. Basic examples of these communities are prisons, but certain urban/rural communities, some schools, among others could possibly fit well into this definition. These communities present a sort of ideal conditions for TB spread. In order to describe key relevant dynamics of the disease in these communities, we consider a five compartments SEIR model with five possible routes toward TB infection: primary infection after a contact with infected and infectious individuals (fast TB), endogenous reactivation after a period of latency (slow TB), relapse by natural causes after a cure, exogenous reinfection of latently infected, and exogenous reinfection of recovered individuals. We discuss the possible existence of multiple endemic equilibrium states and the role that the two types of exogenous reinfections in the long-term dynamics of the disease could play
dc.language.iso en_US
dc.subject Exogenous reinfection
dc.subject Mycobacterium-Tuberculosis
dc.subject Pulmonary Tuberculosis
dc.subject Epidemiology
dc.subject Infection
dc.subject Transmission
dc.subject Immigration
dc.subject Dynamics
dc.subject Risk
dc.title Modeling the Spread of Tuberculosis in Semiclosed Communities
dc.type Artículo


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