Correlation in radiological bone age determination using the Greulich and Pyle method versus automated evaluation using BoneXpert software
Date
2018
Type:
Article
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Abstract
Objective: To determine the degree of correlation in the radiological bone age assessment using the Greulich and Pyle method versus automated assessment through BoneXpert® software between 2013 and 2016. Material and Method: Correlation study of diagnostic techniques of 1500 carpal X-rays to assess bone age in patients under 16 years of age from Clínica Alemana de Santiago. X-rays with bone age assessment using the Atlas of Greulich and Pyle (GP) by 1 out of 7 pediatric radiologists, were analyzed using the BoneXpert (BE) software for automated bone age assessment. 100 cases were
taken at random for analysis/re-analysis using the BoneXpert method to determine its accuracy. The level of correlation of the measurements was analyzed using the correlation coefficient (Pearson’s r) and the variability of the measurements using the Bland-Altman analysis. Results: 1493 cases were assessed, seven were excluded due to failure in the X-ray technique, 922 females (61.8%), with a median chronological age of 9.96 years and 11.12 years for males (p 0.001). The correlation between manual bone age (GP) and automated bone age using BoneXpert method among radiologists ranged from 0.91 to 0.93. The Bland-Altman analysis indicated an average difference between manual
bone age and bone age using the BoneXpert method of 0.19 years (CI 0.13 to 0.25). In the analysis/re-analysis of 100 random cases using the BoneXpert software, the correlation was 1.00 (100% accuracy). Conclusion: The automated analysis using BoneXpert allows for standardized, low-variability, and high-concordance assessment.
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Citation
Pose Lepe Georgette, Villacrés Fabián, Silva Fuente-Alba Claudio, Guiloff Stefan. Correlation in radiological bone age determination using the Greulich and Pyle method versus automated evaluation using BoneXpert software. Rev. chil. pediatr. [Internet]. 2018 Oct [cited 2022 May 23] ; 89( 5 ): 606-611. Available from: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062018000500606&lng=en. http://dx.doi.org/10.4067/S0370-41062018005000705.
Keywords
Bone age measurement, Greulich and Pyle, BoneXpert