Tesis Doctorales

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Identification of germline genetic variants in miRNA genes targeting BRCA 1/2 genes and their role in chilean familial breast cancer risk : searching for novel findings

Mayo Glaser, Tomas Gabriel de (Universidad del Desarrollo. Facultad de Medicina, 2018)

Breast cancer (BC) is the most common cancer in women worldwide and the second most common malignancy as a whole, therefore constituting an important cause of death and a severe burden for public health systems. During the ...
Regulación de la enzima 11 beta hidroxiesteroide deshidrogenasa tipo 2 [11ß-HSD2] por miRNA y su asociación con hipertensión arterial

Tapia Castillo, Alejandra (Universidad del Desarrollo. Facultad de Medicina, 2018)

Classical apparent mineralocorticoid excess (AME) is a rare recessive disorder, caused by 11β-HSD2 deficiency. AME manifests as low-renin pediatric hypertension, hypokalemia and high cortisol/cortisone (F/E) ratio. The ...