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Transcranial doppler as a predictor of ischemic events in carotid artery dissection

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dc.contributor.author Brunser, Alejandro
dc.contributor.author Lavados, Pablo
dc.contributor.author Hoppe, Arnold
dc.contributor.author Muñoz-Venturelli, Paula
dc.contributor.author Sujima, Emi
dc.contributor.author Lopez, Javiera
dc.contributor.author Eloy, Mansilla
dc.contributor.author Carcamo, Daniel
dc.contributor.author Diaz, Violeta
dc.date.accessioned 2017-09-11T16:02:15Z
dc.date.available 2017-09-11T16:02:15Z
dc.date.issued 2017
dc.identifier.citation J Neuroimaging. 2017 Mar;27(2):232-236
dc.identifier.uri http://hdl.handle.net/11447/1667
dc.identifier.uri http://dx.doi.org/10.1111/jon.12379
dc.description.abstract Abstract BACKGROUND: We aim to evaluate clinical features and transcranial Doppler (TCD) elements, as predictors of the development of ischemic events (IEs) in patients suffering from spontaneous carotid arterial dissection without stroke (CCADW). METHODS: Consecutive patients with CCADW, seen in Clínica Alemana de Santiago between April 2004 and January 2015, were evaluated clinically, and with TCD, microembolic signals (MES) monitoring and breath hold Index (BHI) test were performed. RESULTS: Forty-one patients with 45 CCADW were included. Mean age 41.9 years, 31 male, and 12 (29.1%) patients present with multiple CCADW. At the moment of TCD evaluation, 17 (41.4%) patients were being treated with antiplatelets and the rest under Heparin. TCD monitoring lasted in average 53.3 minutes and demonstrated at the moment of evaluation, MES in four carotid arteries (11.1%) of 3 patients and 13 (28.8%) abnormal BHI in 11 patients. Six IEs occurred in 3 patients, 3 strokes, and 3 transient ischemic attacks. In the univariate analysis correlating IE with clinical and ultrasonographic findings, the degree of carotid stenosis, the presence of multiple CAD, and the presence of MES plus abnormalities of BHI were significantly associated with the risk of an IE. Multivariable analysis showed that only the presence of MES plus abnormal BHI were significant (P < .001). MES and abnormal BHI were present in the 3 patients and in four arterial territories that had IE. CONCLUSIONS: TCD can identify a subgroup of patients with CCADW who are at high risk of IE.
dc.format.extent 5
dc.language.iso en_US
dc.publisher Wiley
dc.subject Ultrasound
dc.subject cervical artery dissection
dc.subject stroke
dc.subject transcranial Doppler ultrasound
dc.title Transcranial doppler as a predictor of ischemic events in carotid artery dissection
dc.type Artículo


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