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Case−Control Study of Risk Factors for Meningococcal Disease in Chile

Show simple item record Olea, Andrea Matute, Isabel Gonzalez, Claudia Delgado, Iris Poffald, Lucy Pedroni, Elena Alfaro, Tania Hirmas, Macarena Nájera, Manuel Gormaz, Ana Lopez, Dario Sergio, Loayza Ferreccio, Catterina Gallegos, Doris Fuentes, Rodrigo Vial, Pablo Aguilera, Ximena 2017-09-04T18:48:07Z 2017-09-04T18:48:07Z 2017
dc.identifier.citation Emerging Infectious Diseases, Volume 23, Number 7—July 2017
dc.description.abstract An outbreak of meningococcal disease with a case-fatality rate of 30% and caused by predominantly serogroup W of Neisseria meningitidis began in Chile in 2012. This outbreak required a case−control study to assess determinants and risk factors for infection. We identified confirmed cases during January 2012−March 2013 and selected controls by random sampling of the population, matched for age and sex, resulting in 135 case-patients and 618 controls. Sociodemographic variables, habits, and previous illnesses were studied. Analyses yielded adjusted odds ratios as estimators of the probability of disease development. Results indicated that conditions of social vulnerability, such as low income and overcrowding, as well as familial history of this disease and clinical histories, especially chronic diseases and hospitalization for respiratory conditions, increased the probability of illness. Findings should contribute to direction of intersectoral public policies toward a highly vulnerable social group to enable them to improve their living conditions and health.
dc.format.extent 9
dc.language.iso en_US
dc.publisher Centers for Disease Control and Prevention
dc.subject meningococcal disease
dc.subject Neisseria meningitidis
dc.subject Sociodemographic variables
dc.subject clinical histories
dc.subject Chile
dc.title Case−Control Study of Risk Factors for Meningococcal Disease in Chile
dc.type Artículo

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