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Septic shock in ICU: Advanced therapeutics, immunoparalysis and genomics. State of the art

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dc.contributor.author Arriagada, Daniela
dc.contributor.author Donoso, Alejandro
dc.contributor.author Cruces, Pablo
dc.contributor.author Díaz, Franco
dc.date.accessioned 2017-03-31T15:50:29Z
dc.date.available 2017-03-31T15:50:29Z
dc.date.issued 2014
dc.identifier.citation Arch Argent Pediatr 2014;112(4):358-365 es_CL
dc.identifier.uri http://dx.doi.org/10.1590/S0325-00752014000400012 es_CL
dc.identifier.uri http://hdl.handle.net/11447/1076
dc.description.abstract New and important concepts have emerged for the advanced management of the child with septic shock in the recent decades. Attending physicians in the Pediatric intensive care unit must be fully aware of them to improve patient care in the critical care unit. It should be considered the use of immune therapy only in selected groups of patients. Continuous renal replacement therapies are well tolerated and their early use prevents deleterious fluid overload. Removal of inflammatory mediators by using high volume hemofiltration may play a role in hyperdynamic septic patients. The use of plasmapheresis is recommended in patients with thrombocytopenia-associated multiple organ failure. Extracorporeal support use should be considered in those with refractory septic shock despite goals directed therapy. The immunoparalysis has been associated with nosocomial infections and late mortality. The information from genetic markers may allow early intervention and preventive genomics-based medicine. es_CL
dc.format.extent 8 es_CL
dc.language.iso en_US es_CL
dc.publisher Sociedad Argentina de Pediatría es_CL
dc.subject sepsis es_CL
dc.subject septic shock es_CL
dc.subject treatment es_CL
dc.subject resuscitation es_CL
dc.subject extracorporeal support es_CL
dc.subject immunoparalysis es_CL
dc.subject genomics es_CL
dc.title Septic shock in ICU: Advanced therapeutics, immunoparalysis and genomics. State of the art es_CL
dc.title.alternative Shock séptico en la Unidad de Cuidados Intensivos. Terapéutica avanzada, inmunoparálisis y genómica. Estado del arte es_CL
dc.type Artículo es_CL


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