Fascioliasis simulating an intrahepatic cholangiocarcinoma—Case report with imaging and pathology correlation

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Abstract

Human fascioliasis is a rare zoonosis in Chile. Clinically it presents with a highly polymorphous group of symptoms that evolve in two periods. The first, acute or a result of hepatic invasion, lasts 2 weeks to 4 months and is characterized essentially by pain in the right hypochondrium and/or epigastrium, continuous fever and painful hepatomegaly. This clinical picture, associated with eosinophilia and a history of raw watercress consumption, corresponds to the classic presentation of the disease in its initial stage. We report the case of a 57-year-old female patient with no risk factors for and no clinical signs of fascioliasis, with a lesion in the right hepatic lobe compatible with intrahepatic cholangiocarcinoma, studied with computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET-CT). With the clinical suspicion of intrahepatic cholangiocarcinoma, a regulated right hepatectomy was performed, the pathological study of which revealed cholangitis and granulomatous pericholangitis resulting from trematode eggs, compatible with Fasciola hepatica.

Description

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Citation

Losada H, Hirsch M, Guzmán P, Fonseca F, Hofmann E, Alanís M. Fascioliasis simulating an intrahepatic cholangiocarcinoma-Case report with imaging and pathology correlation. Hepatobiliary Surg Nutr. 2015 Feb;4(1):E1-7

Keywords

Fasciola hepatica, Intrahepatic cholangiocarcinoma, Case report, Radiology, Pathology

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