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Increase of pro-oxidants with no evidence of lipid peroxidation in exhaled breath condensate after a 10-km race in non-athletes

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dc.contributor.author Araneda, O
dc.contributor.author Urbina-Stagno, R
dc.contributor.author Tuesta, M
dc.contributor.author Haichelis, D
dc.contributor.author Alvear, M
dc.contributor.author Salazar, M
dc.contributor.author García, C
dc.date.accessioned 2017-04-03T14:31:30Z
dc.date.available 2017-04-03T14:31:30Z
dc.date.issued 2014
dc.identifier.citation J Physiol Biochem. 2014 Mar;70(1):107-15 es_CL
dc.identifier.uri http://dx.doi.org/10.1007/s13105-013-0285-0 es_CL
dc.identifier.uri http://hdl.handle.net/11447/1078
dc.description.abstract It is a well-established fact that exercise increases pro-oxidants and favors oxidative stress; however, this phenomenon has been poorly studied in human lungs. Pro-oxidative generation (H(2)O(2), NO(2) (-)), lipid peroxidation markers (MDA), and inflammation (pH) in exhaled breath condensate (EBC) have been determined through data from 10 active subjects who ran 10 km; samples were obtained immediately before, at 20, and at 80 min post-exertion. In EBC, the concentration of H(2)O(2) at 80 min post-exertion was increased. NO(2) (-) concentration showed a tendency to increase at 80 min post-exertion, with no variations in MDA and pH. No variations of NO(2) (-) were found in plasma, while there was an increase of NO(2) (-) at 80 min post-exertion in the relation between EBC and plasma. NO(2) (-) in EBC did not correlate to plasmatic NO(2) (-), while it did correlate directly with H(2)O(2) in EBC, suggesting a localized origin for the exercise-related NO(2) (-) increase in EBC. MDA in plasma did not increase nor correlate with MDA in EBC. In conclusion, high-intensity exercise increases lung-originated pro-oxidants in non-athlete subjects with no evidence of early lipid peroxidation and changes in the pH value in EBC. es_CL
dc.format.extent 9 es_CL
dc.language.iso en_US es_CL
dc.publisher Springer es_CL
dc.subject Exhaled breath condensate es_CL
dc.subject Runners es_CL
dc.subject Lung oxidative stress es_CL
dc.subject Lung inflammation es_CL
dc.title Increase of pro-oxidants with no evidence of lipid peroxidation in exhaled breath condensate after a 10-km race in non-athletes es_CL
dc.type Artículo es_CL


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